House-dust mite allergen Der p 1: amount or concentration?
| Autor: | Peter H. Howarth, P. Yogeswaran, I. J. M. Doull, J. Bright |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Immunology
Dose-Response Relationship Immunologic Beds medicine.disease_cause Acariformes Allergen Animal science Floors and Floorcoverings medicine Mite Animals Humans Immunology and Allergy Acari Antigens Dermatophagoides Glycoproteins House dust mite Mites biology Chemistry House dust mite allergen Pyroglyphidae Dust Aeroallergen Allergens biology.organism_classification respiratory tract diseases |
| Zdroj: | Allergy. 52:220-223 |
| ISSN: | 1398-9995 0105-4538 |
| DOI: | 10.1111/j.1398-9995.1997.tb00979.x |
| Popis: | There is a lack of consensus as to the best way to quantify settled house-dust mite Der p 1 allergen from planar and nonplanar surfaces. To investigate the most appropriate measure of settled house-dust mite Der p 1 allergen, we determined the relationship between Der p 1 allergen content and collected dust weight from planar-surface (mattress) and nonplanar-surface (living-room) samples in 58 homes. There was a direct relationship between Der p 1 content and dust weight for both planar-surface (mattress, n = 217) samples (r = 0.50, P < 0.0001) and nonplanar-surface (living-room, n = 48) samples (r = 0.61, P < 0.0001). Correction for the surface area of the planar surface (mattress) vacuum-cleaned resulted in no additional benefit. We conclude that expression of Der p 1 levels per weight of collected dust appears to be the best method for both planar and nonplanar surfaces. |
| Databáze: | OpenAIRE |
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