Cochlear tuning estimates from level ratio functions of distortion product otoacoustic emissions

Autor: Jenna Browning-Kamins, Alessandra Spada Durante, Renata Sisto, Arturo Moleti, Uzma Shaheen Wilson, Sumitrajit Dhar, Sriram Boothalingam
Rok vydání: 2021
Předmět:
Zdroj: Int J Audiol
ISSN: 1708-8186
1499-2027
Popis: Distortion product otoacoustic emission (DPOAE) levels plotted as a function of stimulus frequency ratio demonstrate a bandpass shape. This bandpass shape is narrower at higher frequencies compared to lower frequencies and thus has been thought to be related to cochlear mechanical tuning. However, the frequency- and level-dependence of these functions above 8 kHz is largely unknown. Furthermore, how tuning estimates from these functions are related to behavioral tuning is not fully understood. From experiment 1, we report DPOAE level ratio functions (LRF) from seven normal-hearing, young-adults for f(2) = 0.75-16 kHz and two stimulus levels of 62/52 and 52/37 dB FPL. We found that LRFs became narrower as a function of increasing frequency and decreasing level. Tuning estimates from these functions increased as expected from 1-8 kHz. In experiment 2, we compared tuning estimates from DPOAE LRF to behavioral tuning in 24 normal-hearing, young adults for 1 and 4 kHz and found that behavioral tuning generally predicted DPOAE LRF estimated tuning. Our findings suggest that DPOAE LRFs generally reflect the tuning profile consistent with basilar membrane, neural, and behavioral tuning. However, further investigations are warranted to fully determine the use of DPOAE LRF as a clinical measure of cochlear tuning.
Databáze: OpenAIRE