Combined Bilateral Submandibular and Sublingual Swelling, Macroglossus, and Carpal Tunnel Syndrome Caused by Light Chain Amyloidosis
| Autor: | Birgitte Ravn Juhl, Viggo Jønsson, Peter Gimsing, Sissel Vorstrup, Niels Rasmussen |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
Male
Pathology medicine.medical_specialty Biopsy Tongue Diseases Fatal Outcome Predictive Value of Tests medicine Macroglossia Edema Humans Mandibular Diseases Carpal tunnel syndrome Multiple myeloma Aged Aged 80 and over Proteinuria business.industry Amyloidosis Sublingual gland Middle Aged medicine.disease Carpal Tunnel Syndrome Submandibular gland Bence Jones protein medicine.anatomical_structure Otorhinolaryngology Female Immunoglobulin Light Chains medicine.symptom Multiple Myeloma business |
| Zdroj: | Ear, Nose & Throat Journal. 77:95-101 |
| ISSN: | 1942-7522 0145-5613 |
| DOI: | 10.1177/014556139807700207 |
| Popis: | Three cases of light chain kappa amyloidosis in multiple myeloma patients are described with remarkable involvement of the tongue and swelling of the sublingual and submandibular regions, and without signs of nephropathy despite Bence Jones kappa proteinuria. All three patients had carpal tunnel syndrome at the beginning of their disease course and only moderate gastrointestinal involvement. Primarily for prognostic reasons, amyloidosis should be suspected in such cases, even in the presence of these highly unusual manifestations, and the diagnosis should be confirmed by unambigously-positive biopsies. |
| Databáze: | OpenAIRE |
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