| Popis: |
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related death worldwide resulting in between 250,000 to one million deaths per annum. It carries dismal prognosis and the number death is close to the incidence of disease owing to the aggressive nature of this tumor. The incidence of HCC is highest in China, eastern Asia, and Saharan African. The main etiology of HCC in these regions is chronic hepatitis B viral infection. In most Western countries, HCC is mainly related to hepatitis C infection and alcoholic liver disease. Nonalcoholic steato-hepatitis and exposure to aflatoxins are also known risk factors for development of HCC. |
