A new character on the scene of cardiorenal syndrome
| Autor: | Maria Giovanna Russo, Francesco Natale, Emanuela Lo Priore, Paolo Calabrò, Chiara Granato, Luigi Aronne, Alessandro Siciliano, Raffaele Calabrò, Chiara Cirillo, Maria Credendino |
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| Přispěvatelé: | Natale, F, LO PRIORE, E, Aronne, L, Siciliano, A, Credendino, M, Cirillo, C, Granato, C, Calabro', Paolo, Russo, Maria Giovanna, Calabro', Raffaele |
| Rok vydání: | 2011 |
| Předmět: |
Male
Kidney Physiology Chemistry Efferent Pulsatile flow Cardiorenal syndrome Anatomy medicine.disease Pulse pressure medicine.anatomical_structure Pulsatile Flow Internal Medicine medicine Arterial stiffness Energy density Humans Ventricular Function Ankle Brachial Index Female Cardiology and Cardiovascular Medicine Myogenic tone |
| Zdroj: | Hypertension research : official journal of the Japanese Society of Hypertension. 34(9) |
| ISSN: | 1348-4214 |
| Popis: | Arterial stiffness has a strong influence onthe kidney because of the distinctive structureof the renal microcirculation. Certain tissues,such as the brain, heart, skin and skeletalmuscle tissues, contain precapillary arteriolesand metarterioles that disperse the majorityof the mean and pulsatile energy content ofthe advancing pressure and flow waveformbefore it reaches the capillary. In contrast,glomerular capillaries are located betweenafferent and efferent arterioles. Because effer-ent arteriolar resistance is physiologicallygreater than afferent resistance, the meanand pulsatile pressures in the glomerulusare relatively elevated. This high hydrostaticpressure ensures the maintenance of anelevated glomerular filtration fraction, whichis normally B20% of renal plasma flow,but exposes the glomerular capillary topotentially harmful pulsatile pressures ifarterial stiffness and pulse pressure are high.Moreover, the myogenic tone of the afferentarteriole is influenced by pressure pulsatility. |
| Databáze: | OpenAIRE |
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