Structure-based design of bitopic ligands for the µ-opioid receptor

Autor:	Abdelfattah Faouzi, Haoqing Wang, Saheem A. Zaidi, Jeffrey F. DiBerto, Tao Che, Qianhui Qu, Michael J. Robertson, Manish K. Madasu, Amal El Daibani, Balazs R. Varga, Tiffany Zhang, Claudia Ruiz, Shan Liu, Jin Xu, Kevin Appourchaux, Samuel T. Slocum, Shainnel O. Eans, Michael D. Cameron, Ream Al-Hasani, Ying Xian Pan, Bryan L. Roth, Jay P. McLaughlin, Georgios Skiniotis, Vsevolod Katritch, Brian K. Kobilka, Susruta Majumdar
Rok vydání:	2022
Předmět:	Multidisciplinary
Zdroj:	Nature.
ISSN:	1476-4687
Popis:	Mu opioid receptor (µOR) agonists like fentanyl have long been used for pain management, but are considered a major public health concern due to their adverse side effects, including lethal overdose.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::143f7b494fdbc9f2a3c16eb8287e1d82 https://pubmed.ncbi.nlm.nih.gov/36450356 Zobrazit plný text záznamu Full text from SpringerLink