Spatial and temporal disease progression of adult-onset subacute sclerosing panencephalitis
| Autor: | Hartmut Lins, E. Kirches, Knut Dietzmann, Carsten Boltze, C. Mawrin, B. Koenig, T. Heinrichs, Shigeo Murayama |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty biology business.industry Autopsy medicine.disease biology.organism_classification Subacute sclerosing panencephalitis Frontal Lobe Central nervous system disease Measles virus Frontal lobe Disease Progression Humans Medicine Occipital Lobe Subacute Sclerosing Panencephalitis Neurology (clinical) Viral disease Age of onset business Occipital lobe |
| Zdroj: | Neurology. 58:1568-1571 |
| ISSN: | 1526-632X 0028-3878 |
| Popis: | An adult-onset case of subacute sclerosing panencephalitis with occipitofrontal spread of the infection documented clinically and by MRI is reported. Autopsy revealed numerous intranuclear viral inclusions and widespread demyelination in both frontal lobes. In the occipital lobes where the disease started 5 years previously, inclusions were rare, but degenerative tissue changes were prominent. This case underlines the importance of measles virus migration for the progression of this fatal disorder. |
| Databáze: | OpenAIRE |
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