Supplementary Figures 1-19, supplementary methods and extended literature evaluation of the candidate genes from Comprehensive Evaluation of Protein Coding Mononucleotide Microsatellites in Microsatellite-Unstable Colorectal Cancer

Autor: Esa Pitkänen, Lauri A. Aaltonen, Sari Tuupanen, Pia Vahteristo, Jukka-Pekka Mecklin, Jan Böhm, Heikki Järvinen, Laura Renkonen-Sinisalo, Jussi Taipale, Minna Taipale, Eevi Kaasinen, Riku Katainen, Heikki Ristolainen, Kimmo Palin, Mervi Aavikko, Jiri Hamberg, Tomas Tanskanen, Sofie Lundgren, Alexandra E. Gylfe, Johanna Kondelin
Rok vydání: 2023
Popis: Figures describing the following; length distribution of somatic insertions and deletions in the exome sequencing data, coverage of mononucleotide microsatellite sites in both exome and MiSeq sequencing data, mutation frequencies at mononucleotide microsatellite sites in the exome sequencing data, number of somatic deletions and insertions in the exome sequencing data, model p-values, expected -log10(p) values, mutation frequency, significance and normalized allelic fraction (NAF) of the top genes, overlap between validation sets 1,2, and 3, and mapped base pairs in the MiSeq sequencing data as well as the supplementary methods and extended literature evaluation of the candidate genes.
Databáze: OpenAIRE