Giant Eosinophilic Granules in the Chronic Di Guglielmo Syndrome
| Autor: | Harvey E. Finkel, Mark J. Brauer |
|---|---|
| Rok vydání: | 1966 |
| Předmět: |
Pathology
medicine.medical_specialty business.industry Metachromasia Bone Marrow Cells Bone Marrow Examination General Medicine Eosinophils Myeloid neoplasia Bone Marrow Leukemia Myeloid Di Guglielmo Syndrome Immunology Eosinophilic Humans Medicine Leukemia Erythroblastic Acute business Bone Marrow Diseases Large size |
| Zdroj: | New England Journal of Medicine. 274:209-210 |
| ISSN: | 1533-4406 0028-4793 |
| DOI: | 10.1056/nejm196601272740409 |
| Popis: | WHILE examining the Wright-Giemsa-stained bone-marrow aspirate of a patient with a chronic myeloproliferative disorder of the Di Guglielmo type, we were struck by the remarkably large size of the granules in the eosinophils. Many were more than four times the normal size, exceeding 2 miera in diameter. Most of the granules were of an orange hue, but some metachromasia was present. The cells, although bizarre, manifested the usual morphologic appearance and maturation of eosinophilic granulocytes, rather than that of cells containing inclusions as a result of secretory or phagocytic activity. This finding was present on all the smears of 3 . . . |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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