Cholesterol Granuloma of the Middle Ear in Post-Irradiated Nasopharyngeal Carcinoma Patients
| Autor: | Maojin Liang, Yaodong Xu, Zhigang Zhang, Yiqing Zheng, Sui-Jun Chen, Haidi Yang, Xiang Liu |
|---|---|
| Rok vydání: | 2011 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Mastoidectomy Mastoid Tympanoplasty otorhinolaryngologic diseases medicine Humans Radiation Injuries Contraindication Aged Granuloma Cholesteatoma Middle Ear Radiotherapy business.industry Cholesteatoma Nasopharyngeal Neoplasms Middle Aged medicine.disease Surgery Radiation therapy Otitis Media Cholesterol Treatment Outcome medicine.anatomical_structure Otorhinolaryngology Nasopharyngeal carcinoma Quality of Life Middle ear Female sense organs business Eardrum |
| Zdroj: | ORL. 73:343-347 |
| ISSN: | 1423-0275 0301-1569 |
| Popis: | Background/Aims: To evaluate the surgical outcome of tympanoplasty with mastoidectomy for cholesterol granuloma of the middle ear in post-irradiated patients with nasopharyngeal carcinoma (NPC). Methods: Nine post-irradiated NPC patients diagnosed with cholesterol granuloma in a single-sided middle ear were included in this study. The time from radiotherapy termination to surgery ranged from 6 to 14 years (median 9 years). All patients underwent radical tympanoplasty with canal wall down or up mastoidectomy. Results: All the patients with NPC received radiotherapy of 68–75 Gy before surgery. Three ears underwent tympanoplasty with canal wall down mastoidectomy, and 6 ears underwent tympanoplasty with canal wall up mastoidectomy. All the patients were followed up for at least 2 years. Seven ears (77.8%) had an intact tympanic membrane and 2 ears developed re-perforation of the eardrum 3 months after surgery, but otorrhea decreased significantly. All these patients reported improved quality of life after surgery. Before the operation, the pure tone averages (0.25, 0.5, 1, 2 kHz) were 90.5 dB and the air-bone gaps (0.5, 1, 2 kHz) were 45.8 dB (vs. 62.3 and 25.5 dB, respectively, at 6 months after the operation). Conclusions: Most post-irradiated NPC patients with cholesterol granuloma of the middle ear benefit from this surgery. Chronic otitis media caused by radiotherapy is not a contraindication to tympanoplasty. |
| Databáze: | OpenAIRE |
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