Ultra-wide-field autofluorescence imaging in non-traumatic rhegmatogenous retinal detachment
Autor: | Szilard Kiss, Minhee Cho, Donald J. D'Amico, G Favarone, R.V. Paul Chan, Matthew T. Witmer |
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Rok vydání: | 2012 |
Předmět: |
Adult
Male medicine.medical_specialty Visual acuity genetic structures medicine.medical_treatment Vitrectomy Endotamponade Retina chemistry.chemical_compound Eye Injuries medicine Humans Fluorescein Angiography Aged Retrospective Studies Aged 80 and over Fluorocarbons medicine.diagnostic_test business.industry Retinal Detachment Retinal detachment Retrospective cohort study Retinal Middle Aged Fluorescein angiography medicine.disease eye diseases Surgery Scleral Buckling Ophthalmology Autofluorescence medicine.anatomical_structure chemistry Clinical Study Female sense organs medicine.symptom business |
Zdroj: | Eye. 26:1209-1216 |
ISSN: | 1476-5454 0950-222X |
DOI: | 10.1038/eye.2012.122 |
Popis: | Rhegmatogenous retinal detachment (RRD) affects the function of the retina before and after surgical repair. We investigated ultra-wide-field autofluorescence (UAF) abnormalities in patients with acute RRD to improve our understanding of the functional changes in the retina before and after surgery. In this retrospective study, we present the UAF imaging findings of 16 patients with acute, non-traumatic RRD. Imaging was obtained with the Optos 200 Tx (Optos) in 14 eyes preoperatively and in 12 eyes postoperatively. Twelve eyes had RRDs that involved the macula (group A), whereas four eyes had macula-sparing RRDs (group B). All patients (100%) with bullous retinal detachments demonstrated hypofluorescence over the area of retinal detachment. A hyperfluorescent leading edge (HLE) to the retinal detachment was observed preoperatively in 100% of eyes in group A and 75% of eyes in group B. Preoperative UAF through the fovea of group A eyes was normal (30%), hypofluorescent (50%) or hyperfluorescent (20%). In all patients with a HLE preoperatively, the HLE resolved by the 1-month postoperative visit. A residual line of demarcation remained in 8 of the 12 eyes (67%). In group A eyes, postoperative granular autofluorescent changes were present in four of the nine (44%) eyes, and were associated with worse preoperative (P=0.04) and postoperative (P=0.09) visual acuity. UAF imaging reveals abnormalities in RRDs that allow excellent demarcation of the extent of the retinal detachment and assist in preoperative characterization of the detachment and postoperative counselling. |
Databáze: | OpenAIRE |
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