Heart rate dynamics in temporal lobe epilepsy—A long-term follow-up study

Autor: Ville Suorsa, Juha T. Korpelainen, Jouko I. T. Isojärvi, Eija Suorsa, Heikki V. Huikuri, Hanna Ansakorpi, Vilho V. Myllylä
Rok vydání: 2011
Předmět:
Zdroj: Epilepsy Research. 93:80-83
ISSN: 0920-1211
DOI: 10.1016/j.eplepsyres.2010.10.005
Popis: The aim of the present study was to prospectively evaluate long-term changes in interictal heart rate variability (HRV) in patients with temporal lobe epilepsy (TLE). A 24-h ECG was recorded at baseline and after a mean follow-up of 6.1 years in 18 patients with refractory TLE and 18 patients with well-controlled TLE. After the follow-up, the Poincare components SD(1) (p=0.039) and SD(2) (p=0.001) were decreased in patients with refractory TLE compared to baseline, whereas in patients with well-controlled TLE no changes (p>0.05) in HR variability were observed. The reduction in HRV seems to be progressive in patients with chronic refractory TLE with recurrent seizures.
Databáze: OpenAIRE