OBSERVATIONS ON THE EFFECTS OF PREPARTAL AND POSTPARTAL ESTROGEN AND PROGESTERONE TREATMENT ON LACTATION IN THE RAT
| Autor: | Sheppard M. Walker, John I. Matthews |
|---|---|
| Rok vydání: | 1949 |
| Předmět: |
endocrine system
medicine.medical_specialty medicine.drug_class Ovary Biology Inhibitory postsynaptic potential Progestogen hormone therapy Endocrinology Internal medicine Lactation medicine Animals Humans Progesterone reproductive and urinary physiology urogenital system Estrogens Rats medicine.anatomical_structure Estrogen Progesterone treatment Female hormones hormone substitutes and hormone antagonists Hormone |
| Zdroj: | Endocrinology. 44:8-17 |
| ISSN: | 1945-7170 0013-7227 |
| DOI: | 10.1210/endo-44-1-8 |
| Popis: | Numerous attempts to determine the relation of hormones to the initiation of lactation following parturition have been made. The onset of lactation has been attributed to removal of an inhibitory action of progesterone, estrogen or a combination of progesterone and estrogen. The establishment of lactation following the removal of corpora lutea in the rabbit (Hammond, 1917) and following the removal of luteinized ovaries in the rat (Selye, Collip and Thomson, 1933) suggested an inhibitory action of the secretion of the corpora lutea but injection of extract of the corpora lutea (Anselmino and Hoffmann, 1936) and progesterone (Folley and Kon, 1937a) in lactating rats failed to inhibit established lactation. The report of Parkes and Bellerby (1927) demonstrated an inhibitory action of estrogens on established lactation in the rat with intact ovaries. Folley and Kon (1937b), Edelmann and Gaunt (1941) and Barsantini and Masson (1947) have shown that inhibition of established lactation by estrogens is more effe... |
| Databáze: | OpenAIRE |
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