| Autor: |
Juergen Schrezenmeir, Christoph D. Garlichs, André Reis, Patrick Linsel-Nitschke, Jennifer Freyer, Thomas Illig, Christina Loley, Klaus Stark, Hendrik B. Sager, Angela Doering, Christian Gieger, Arif B. Ekici, Petra Belcredi, A. Reinhardt, A Grosshennig, Stephanie Tennstedt, N Klopp, Thomas Meitinger, N. E. El Mokhtari, Diana Rubin, Andreas Ziegler, Arne Schäfer, Zouhair Aherrahrou, Petra Bruse, Jens Baumert, Janja Nahrstaedt, Heribert Schunkert, Heinz Erich Wichmann, Annette Peters, Wolfgang Lieb, Anja Medack, Jeanette Erdmann, Michael Preuss, Arnika Kathleen Wagner, Christa Meisinger, Christina Willenborg, Inke R. König, Dorette Raaz-Schrauder, Stefan Schreiber, Christian Hengstenberg |
| Jazyk: |
angličtina |
| Rok vydání: |
2010 |
| Předmět: |
|
| Zdroj: |
European Heart Journal
European Heart Journal; Vol 32 |
| ISSN: |
1522-9645
0195-668X |
| DOI: |
10.1093/eurheartj/ehq405 |
| Popis: |
Aims Recent genome-wide association (GWA) studies identified 10 chromosomal loci for coronary artery disease (CAD) or myocardial infarction (MI). However, these loci explain only a small proportion of the genetic variability of these pertinent diseases. We sought to identify additional CAD/MI loci by applying a three-stage approach. Methods and results We genotyped n = 1157 MI cases and n = 1748 controls from a population-based study population [German MI Family Study (GerMIFS) III (KORA)] with genome-wide SNP arrays. At this first stage, n = 462 SNPs showed association with MI at P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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