Acaricidal activities of the essential oil from Rhododendron nivale Hook. f. and its main compund, δ-cadinene against Psoroptes cuniculi
| Autor: | Xu Zheng Zhou, Xiaofei Shang, Xiao Guo, Jiyu Zhang, Bing Li, Wen Hao |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Veterinary medicine Mite Infestations Rhododendron Biology Gas Chromatography-Mass Spectrometry law.invention Terpene 03 medical and health sciences chemistry.chemical_compound Ivermectin law Botany medicine Oils Volatile Animals Petroleum ether Psoroptes cuniculi Essential oil Acaricides Polycyclic Sesquiterpenes Chloroform General Veterinary Acaricide Plant Extracts Psoroptidae General Medicine 030108 mycology & parasitology chemistry Shoot Parasitology Rabbits Sesquiterpenes medicine.drug |
| Zdroj: | Veterinary parasitology. 236 |
| ISSN: | 1873-2550 |
| Popis: | In this paper, the acaricidal activities of Rhododendron nivale Hook. f. and its main compound, δ-cadinene were investigated, and the chemical composition of the essential oil was analyzed. The results showed that among aqueous, 70% ethanols, acetic ether, chloroform, petroleum ether and essential oil extracts from the shoots and leaves, the essential oil showed the best in vitro acaricidal activity against adult P. cuniculi, which occurred in a concentration- and time-dependent manner. The median lethal time (LT50) values of four concentrations (33.33-4.17mg/ml) of the essential oil ranged from 1.476 to 25.900h, respectively. After the treatment of P. cuniculi with the essential oil and ivermectin, infected rabbits were free of scabs or secretions in the ear canal by day 20. Then, the percent yield of essential oil from the leaves and shoots was 2.45% (w/w), which includes 50 compounds. The primary component identified was terpenes, and among of compounds identified from the essential oil of R. nivale the highest relative content was δ-cadinene, which also presented the marked acaricidal activity against Psoroptes cuniculi in vitro. These findings provide evidence for the use of acaricides as a traditional medicine and indicate that the essential oil and δ-cadinene could be used to control mites in livestock. |
| Databáze: | OpenAIRE |
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