The Cardiovascular Effects of Nitrous Oxide-Halothane Anesthesia in Man
Autor: | T. H. Cromwell, N. T. Smith, D. C. Sawyer, M. J. Halsey, Edmond I. Eger, S. H. Bahlman, Thomas F. Shakespeare, W. C. Stevens |
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Rok vydání: | 1971 |
Předmět: |
Adult
Male inorganic chemicals Sympathetic Nervous System Time Factors Nitrous Oxide Blood Pressure Halothane anesthesia Cardiovascular System Body Temperature Hemoglobins chemistry.chemical_compound Oxygen Consumption Heart Rate Humans Medicine Cardiac Output business.industry Muscles organic chemicals Hemodynamics Nitrous oxide equipment and supplies Stimulation Chemical Anesthesiology and Pain Medicine Hematocrit chemistry Regional Blood Flow Depression Chemical Anesthesia Anesthetic bacteria Vascular Resistance Anesthesia Inhalation Halothane business medicine.drug |
Zdroj: | Anesthesiology. 35:274-284 |
ISSN: | 0003-3022 |
DOI: | 10.1097/00000542-197109000-00010 |
Popis: | The cardiovascular effects of nitrous oxide-halo-thane-oxygen anesthesia were studied in eight unpremedicated healthy male volunteers and the results compared with those obtained in previous studies in which only halothane-oxygen anesthesia was used. Adding nitrous oxide to halothane-oxygen anesthesia resulted in less depression of the cardiovascular system than comparable levels of halothane-oxygen anesthesia. The differences were greatest at light levels of anesthesia and early in the anesthetic course. Most of the differences between the nitrous oxide and non-nitrous oxide groups were abolished at deeper levels of halothane anesthesia or after five hours of anesthesia had elapsed. Body temperature increased an average of 0.3 C with increasing depth of halothane anesthesia when nitrous oxide was present. The effect of discontinuing nitrous oxide for 15 minutes was also compared with data from a previous study in which nitrous oxide was added to halothane-oxygen anesthesia. The results seem to conform a sympathetic stimulating action of nitrous oxide. |
Databáze: | OpenAIRE |
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