The significance of CA125 levels in patients with chronic congestive heart failure. Correlation with clinical and echocardiographic parameters
| Autor: | Eleni M. Kalkandi, Dimitris K. Babalis, Nikos T. Kouris, Georgia S. Goranitou, Ioannis D. Zacharos, Haris E. Grassos, Maria D. Sifaki, D. D. Kontogianni |
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| Rok vydání: | 2003 |
| Předmět: |
Male
medicine.medical_specialty endocrine system diseases Heart Ventricles Renal function Doppler echocardiography Severity of Illness Index Cohort Studies Internal medicine Edema Severity of illness medicine Ventricular Pressure Humans cardiovascular diseases Aged Ultrasonography Aged 80 and over Heart Failure Ejection fraction medicine.diagnostic_test business.industry Stroke Volume Middle Aged medicine.disease Heart failure CA-125 Antigen cardiovascular system Ventricular pressure Cardiology Liver function medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | European journal of heart failure. 7(2) |
| ISSN: | 1388-9842 |
| Popis: | Objective: To assess serum levels of carbohydrate antigen 125 (CA125) in patients with chronic congestive heart failure (CHF) and to assess any correlation with clinical symptoms and echocardiographic indices. Patients and methods: We enrolled 77 male patients (mean age: 73±10 years) admitted to the Cardiology Emergency Department (ED) with cardiac symptoms requiring hospitalization. Diagnosis of CHF was based upon medical history or initial echocardiographic evaluation on current admission. Serum CA125 was measured by an enzyme immunoradiometric assay, on admission and before discharge. Results: The median overall CA125 value was 22.4 (11.5−48.9) U/ml. Serum CA125 levels were related to the severity of CHF [New York Heart Association (NYHA) class I: 19.2 (7.2−31) U/ml, NYHA class II: 17.6 (10−23) U/ml, NYHA class III: 32 (25−77) U/ml and NYHA class IV: 34.3 (18.6−77) U/ml (p |
| Databáze: | OpenAIRE |
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