Nachweis einer fehlenden Kontaktinhibition der Leber durch Northern blot und Array-Technik bei der congenitalen Zwerchfellhernie im Nitrofen-Rattenmodell

Autor:	J. R. Izbicki, W. Lambrecht, T. E. Langwieler, Oliver Mann, Dietrich Kluth
Rok vydání:	2003
Předmět:	Pathology medicine.medical_specialty Thoracic cavity business.industry Congenital diaphragmatic hernia Hypoxia (medical) Liver parts medicine.disease medicine.anatomical_structure Fetal circulation Pediatric surgery medicine Diaphragmatic hernia medicine.symptom business Hypoplastic lung
Zdroj:	Deutsche Gesellschaft für Chirurgie ISBN: 9783540006596 Zurück in die Zukunft ISBN: 9783540200024
DOI:	10.1007/978-3-642-19024-7_154
Popis:	Background Symptoms of congenital diaphragmatic hernia has to be a central theme in pediatric surgery. An attempt to operate these children in case of an ultrasonically detected diaphragmatic hernia during the fetal period was unsuccessful. The main problems are the hypoplastic lungs, the hypoxia and at last the persisting fetal circulation that is responsible for the death of the children. In prior investigations we detected first that there is an active in growths of the liver in the thoracic cavity and second an increased proliferation of the intrathoracic part of the liver (BrdU-labeling-index). In this study we focused mainly to the difference in gene expression of the different liver parts.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13fd6b52c2b83b328b1d25fbdee44c73 https://doi.org/10.1007/978-3-642-19024-7_154 Zobrazit plný text záznamu