Wuchereria bancrofti in Tanzania: microfilarial periodicity and effect of blood sampling time on microfilarial intensities
| Autor: | Dan W. Meyrowitsch, Lea Niemann, Paul E. Simonsen |
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| Rok vydání: | 1997 |
| Předmět: |
Adult
Male Biology Nocturnal Parasitemia medicine.disease_cause Tanzania Statistics medicine Animals Humans Wuchereria bancrofti Microfilariae Public Health Environmental and Occupational Health Middle Aged Peripheral blood Circadian Rhythm Filariasis Intensity (physics) Infectious Diseases Immunology Female Parasitology Sampling time Blood sampling |
| Zdroj: | Tropical Medicine and International Health. 2:153-158 |
| ISSN: | 1365-3156 1360-2276 |
| DOI: | 10.1046/j.1365-3156.1997.d01-237.x |
| Popis: | The circadian periodicity of Wuchereria bancrofti microfilarial (mf) intensities in peripheral blood was analysed in a group of infected individuals from an endemic community in north-eastern Tanzania. The mf density was quantified at two-hourly intervals for 24 hours. A clear nocturnal periodic pattern was observed. Mathematical analysis of the data indicated a peak at 0152 h and a periodicity index of 117.5. A periodicity equation was developed describing the average relation between mf intensity and hour of the day for the study area. Based on the observed periodicity pattern, the effect of blood sampling before peak time is discussed, and the importance of taking sampling time into consideration when analysing data from epidemiological studies is emphasized. A simple method is devised which can be used to adjust for the influence of time on mf intensities, in studies where accurate information on mf intensities is necessary, and where it is impossible to obtain all samples at peak time. |
| Databáze: | OpenAIRE |
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