Metastatic cutaneous melanoma associated with vitreous seeding
| Autor: | Roderick Francis Justin O Day, John Benedict Clark, John Ross Rocke, Lauren Christina Giudicatti |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
lcsh:R5-920
Pathology medicine.medical_specialty Metastatic Cutaneous Melanoma business.industry ocular metastases General Medicine Metastatic melanoma 030204 cardiovascular system & hematology Vitreous seeding targeted therapy BRAF 03 medical and health sciences 0302 clinical medicine new treatments cancer Medicine 030212 general & internal medicine lcsh:Medicine (General) business |
| Zdroj: | Australasian Medical Journal, Vol 10, Iss 7, Pp 571-574 (2017) |
| ISSN: | 1836-1935 |
| DOI: | 10.21767/amj.2017.2959 |
| Popis: | Background Ocular metastases of cutaneous melanoma exclusive to the vitreous are a rare presentation and usually represent disseminated disease. Although traditionally associated with poor outcomes, recent developments in melanoma treatment have vastly improved prognosis. Aims To review new targeted therapies for metastatic-melanoma. Methods Literature review of current clinical guidelines, systematic reviews and case series surrounding current recommended targeted therapies for metastatic-melanoma. Results New targeted therapeutic agents offer improved treatment response, progression free survival, overall survival and have a better side-effect profile than traditional chemotherapy agents for metastatic melanoma. Conclusion Targeted agents for melanoma have improved patient prognosis and life expectancy, likely leading to reduced need for surgical intervention. |
| Databáze: | OpenAIRE |
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