Sustained lung inflation at birth via short binasal prong in very low birth weight preterm infants: A retrospective study

Autor: Mehmet Büyüktiryaki, Nilüfer Okur, Buse Ozer Bekmez, Fuat Emre Canpolat, Handan Bezirganoglu, Gülsüm Kadıoğlu Şimşek, Cüneyt Tayman, Suna Oguz, Hayriye Gozde Kanmaz
Rok vydání: 2018
Předmět:
Pulmonary and Respiratory Medicine
Male
Pediatrics
medicine.medical_specialty
medicine.medical_treatment
Gestational Age
behavioral disciplines and activities
03 medical and health sciences
0302 clinical medicine
Risk Factors
030225 pediatrics
medicine
Poractant alfa
Humans
Infant
Very Low Birth Weight
030212 general & internal medicine
Continuous positive airway pressure
Phospholipids
Bronchopulmonary Dysplasia
Retrospective Studies
Mechanical ventilation
Biological Products
Respiratory Distress Syndrome
Newborn
Respiratory distress
Continuous Positive Airway Pressure
business.industry
Infant
Newborn
Gestational age
Insufflation
Pulmonary Surfactants
medicine.disease
Respiration
Artificial
Low birth weight
Bronchopulmonary dysplasia
Pediatrics
Perinatology and Child Health
Gestation
Female
medicine.symptom
business
Infant
Premature
medicine.drug
Zdroj: Pediatric pulmonology. 53(10)
ISSN: 1099-0496
Popis: BACKGROUND AND OBJECTIVES It is believed, that sustained lung inflation (SLI) at birth in preterm infants reduces the need for mechanical ventilation (MV) and improves respiratory outcomes. The aim of this study was to compare need for MV in preterm infants at high risk for respiratory distress syndrome (RDS) after prophylactic SLI via short binasal prongs at birth combined with early nasal continuous positive airway pressure (nCPAP) versus nCPAP alone. METHODS Medical records of infants born at 260/7 to 296/7 weeks gestation through 2015 and 2017 were retrospectively assessed. Infants who get sustained inflations at 25 cmH2 O pressure for 15 s following delivery via binasal short prongs comprised the study group. Gestational age matched infants who was supported solely with nCPAP (6 cmH2 O PEEP) comprised the control group. Early rescue surfactant (200 mg/kg poractant alfa) was delivered using the less invasive surfactant administration technique in infants with established RDS. RESULTS A total of 215 infants were analyzed. Fewer infants in the SLI group required MV within the first 72 h of life compared to the control group (25.7% vs 56.9%, P
Databáze: OpenAIRE
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