Subjective cognitive decline and rates of incident Alzheimer's disease and non–Alzheimer's disease dementia
| Autor: | Slot, Rosalinde E R, Sikkes, Sietske A M, Lista, Simone, Luck, Tobias, Maruff, Paul, Molinuevo, José Luis, Kornhuber, Johannes, Reisberg, Barry, Riedel-Heller, Steffi G, Risacher, Shannon L, Roehr, Susanne, Sachdev, Perminder S, Berkhof, Johannes, Scarmeas, Nikolaos, Scheltens, Philip, Shulman, Melanie B, Saykin, Andrew J, Verfaillie, Sander C J, Visser, Pieter Jelle, Vos, Stephanie J B, Wagner, Michael, Wolfsgruber, Steffen, Jessen, Frank, Brodaty, Henry, Initiative, Alzheimer's Disease Neuroimaging, group, DESCRIPA working, group, INSIGHT-preAD study, group, SCD-I working, van der Flier, Wiesje M, Boada, Mercè, de Deyn, Peter Paul, Jones, Roy, Frisoni, Giovanni, Spiru, Luiza, Buckley, Rachel, Nobili, Flavio, Freund-Levi, Yvonne, Soininen, Hilkka, Verhey, Frans, Wallin, Åsa K, Touchon, Jacques, Rikkert, Marcel Olde, Rigaud, Anne-Sophie, Bullock, Roger, Tsolaki, Magda, Cavedo, Enrica, Vellas, Bruno, Wilcock, Gordon, Hampel, Harald, Froelich, Lutz, Bakardjian, Hovagim, Benali, Habib, Bertin, Hugo, Bonheur, Joel, Boukadida, Laurie, Boukerrou, Nadia, Dardiotis, Efthimios, Chiesa, Patrizia, Colliot, Olivier, Dubois, Bruno, Dubois, Marion, Epelbaum, Stéphane, Gagliardi, Geoffroy, Genthon, Remy, Habert, Marie-Odile, Guillo-Benarous, Francoise, Houot, Marion, Kas, Aurélie, Lamari, Foudil, Levy, Marcel, Metzinger, Christiane, Mochel, Fanny, Nyasse, Francis, Poisson, Catherine, Potier, Marie-Claude, Revillon, Marie, Santos, Antonio, Andrade, Katia Santos, Sole, Marine, Surtee, Mohmed, Thiebaud de Schotten, Michel, Vergallo, Andrea, Younsi, Nadjia, Kochan, Nicole A |
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| Přispěvatelé: | Psychiatrie & Neuropsychologie, RS: MHeNs - R1 - Cognitive Neuropsychiatry and Clinical Neuroscience, DESCRIPA working group, INSIGHT-preAD study group, SCD-I working group, Neurology, Amsterdam Neuroscience - Neurodegeneration, Epidemiology and Data Science, APH - Methodology, APH - Personalized Medicine, Clinical Neuropsychology |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Male NATIONAL INSTITUTE Pediatrics epidemiology [Cognitive Dysfunction] Epidemiology Dementia incidence Preclinical Alzheimer's disease Vascular dementia Cohort Studies 0302 clinical medicine RECRUITMENT METHODS Risk Factors Cognitive decline Aged 80 and over Health Policy Incidence Hazard ratio Middle Aged Alzheimer's disease IMPAIRMENT 3. Good health Psychiatry and Mental health Disease Progression Female psychology [Cognitive Dysfunction] ASSOCIATION WORKGROUPS Alzheimer’s disease Frontotemporal dementia Alzheimer's Disease Neuroimaging Initiative MAJOR SUBTYPES medicine.medical_specialty psychology [Dementia] epidemiology [Dementia] Dementia Lewy bodies Article APOLIPOPROTEIN-E 03 medical and health sciences Cellular and Molecular Neuroscience Diagnostic Self Evaluation Developmental Neuroscience SDG 3 - Good Health and Well-being BASE-LINE CHARACTERISTICS Subjective cognitive decline Neurology (clinical) Geriatrics and Gerontology Psychiatry and Mental Health medicine Dementia Humans Cognitive Dysfunction ddc:610 OLDER-ADULTS Preclinical Alzheimer’s disease Aged Proportional hazards model business.industry Memory clinic medicine.disease Self Concept 030104 developmental biology DIAGNOSTIC GUIDELINES Human medicine business MEMORY COMPLAINTS 030217 neurology & neurosurgery |
| Zdroj: | Slot, R E R, Sikkes, S A M, Berkhof, J, Brodaty, H, Buckley, R, Cavedo, E, Dardiotis, E, Guillo-Benarous, F, Hampel, H, Kochan, N A, Lista, S, Luck, T, Maruff, P, Molinuevo, J L, Kornhuber, J, Reisberg, B, Riedel-Heller, S G, Risacher, S L, Roehr, S, Sachdev, P S, Scarmeas, N, Scheltens, P, Shulman, M B, Saykin, A J, Verfaillie, S C J, Visser, P J, Vos, S J B, Wagner, M, Wolfsgruber, S, Jessen, F, Bakardjian, H, Benali, H, Vergallo, A, Younsi, N, Alzheimer's Disease Neuroimaging Initiative, DESCRIPA working group, INSIGHT-preAD study group, SCD-I working group & van der Flier, WM 2019, ' Subjective cognitive decline and rates of incident Alzheimer's disease and non–Alzheimer's disease dementia ', Alzheimer's and Dementia, vol. 15, no. 3, pp. 465-476 . https://doi.org/10.1016/j.jalz.2018.10.003 Alzheimer's & Dementia, 15(3), 465-476. Elsevier Science Alzheimer's & dementia : the journal of the Alzheimer's Association Alzheimer's Disease Neuroimaging Initiative, DESCRIPA working group, INSIGHT-preAD study group & SCD-I working group 2019, ' Subjective cognitive decline and rates of incident Alzheimer's disease and non–Alzheimer's disease dementia ', Alzheimer's and Dementia, vol. 15, no. 3, pp. 465-476 . https://doi.org/10.1016/j.jalz.2018.10.003 Alzheimer's & dementia Alzheimer's and dementia 15(3), 465-476 (2018). doi:10.1016/j.jalz.2018.10.003 Alzheimer's and Dementia, 15(3), 465-476. Elsevier Alzheimer's and Dementia, 15(3), 465-476. Elsevier Inc. |
| ISSN: | 1552-5260 |
| Popis: | Introduction: In this multicenter study on subjective cognitive decline (SCD) in community-based and memory clinic settings, we assessed the (1) incidence of Alzheimer's disease (AD) and non-AD dementia and (2) determinants of progression to dementia.Methods: Eleven cohorts provided 2978 participants with SCD and 1391 controls. We estimated dementia incidence and identified risk factors using Cox proportional hazards models.Results: In SCD, incidence of dementia was 17.7 (95% Poisson confidence interval 15.2-20.3)/1000 person-years (AD: 11.5 [9.6-13.7], non-AD: 6.1 [4.7-7.7]), compared with 14.2 (11.3-17.6) in controls (AD: 10.1 [7.7-13.0], non-AD: 4.1 [2.6-6.0]). The risk of dementia was strongly increased in SCD in a memory clinic setting but less so in a community-based setting. In addition, higher age (hazard ratio 1.1 [95% confidence interval 1.1-1.1]), lower Mini-Mental State Examination (0.7 [0.66-0.8]), and apolipoprotein E epsilon 4 (1.8 [1.3-2.5]) increased the risk of dementia.Discussion: SCD can precede both AD and non-AD dementia. Despite their younger age, individuals with SCD in a memory clinic setting have a higher risk of dementia than those in community-based cohorts. (C) 2018 The Authors. Published by Elsevier Inc. |
| Databáze: | OpenAIRE |
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