A Multi-centre Survey of Acceptability of Newborn Screening for Sickle Cell Disease in Nigeria
| Autor: | Ijeoma N. Diaku-Akinwumi, Chinedu C. Okeke, Abjah M. Usman, Modupe T. Balogun, Frédéric B. Piel, Juliana Olufunke J. Lawson, Mustapha Abubakar Jamda, Benard A. Bene, Ngozi Immaculata Ugwu, O W Aworanti, A. A. Okolo, Ifeoma I. Emodi, Biobele J. Brown, Yetunde Tinuola Israel-Aina, Samuel Ademola Adegoke, Hezekiah Isa, John Ayodele Olaniyi, Adekunle Adekile, Osita U Ezenwosu, EC Okocha, Chinatu Ohiaeri, Obiageli E Nnodu, John C Aneke |
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| Jazyk: | angličtina |
| Rok vydání: | 2018 |
| Předmět: |
medicine.medical_specialty
Disease Pediatrics 03 medical and health sciences knowledge and attitude 0302 clinical medicine Social barriers genetic disease 030225 pediatrics acceptability Health care Genetics Medicine health care services Multi centre Newborn screening business.industry General Engineering undergraduate students nigeria health survey Blood Disorder 030220 oncology & carcinogenesis Family medicine health care professionals sickle cell disease Public Health Penicillin prophylaxis business Developed country new-born screening |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | Background Sickle cell disease (SCD) is a major genetic disease that manifests early in life and may lead to significant morbidities. One of the health care services that have been effective in reducing the burden of SCD in developed countries is newborn screening (NBS) followed by pneumococcal vaccines, penicillin prophylaxis, and hydroxyurea treatment. Yet, in sub-Saharan African countries, where about 75% of annual affected babies worldwide are born, NBS programmes are largely unavailable. It is not clear whether this is due to technical challenges associated with setting up such programmes, or significant cultural and social barriers to its acceptance in such settings. Objective Our aim was to ascertain the attitudes to and acceptability of NBS in Nigeria among various socio-demographic groups including health professionals, undergraduate students, parents of children with SCD and SCD patients. Methods Data on socio-demographic characteristics, knowledge of SCD and attitude towards NBS were collected using a semi-structured pre-tested questionnaire from April to July 2014 across 15 health institutions and university campuses in Nigeria. Data were collected from 1,301 respondents across Nigeria. Results There was good knowledge of SCD as an inherited blood disorder. Although 86% of respondents (n = 1,119) supported NBS, there was a statistically significant relationship between support for NBS and age (p = 003), educational status (p = 000) and religion (p = 000). Conclusion This study suggests that there is a good acceptability of NBS across Nigeria. The main barriers to its use are likely to be financial and practical, rather than social or cultural. |
| Databáze: | OpenAIRE |
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