The first 1000 symptomatic pediatric SARS-CoV-2 infections in an integrated health care system: a prospective cohort study
| Autor: | Ryan Moore, Ritu Banerjee, Kathryn Garguilo, Jessica Gillon, Kerry LeBlanc, Henry J. Domenico, Natasha B. Halasa, Leigh M Howard, Jonathan E. Schmitz, Steven A. Webber, Adam C. Seegmiller, Daniel W. Byrne |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
medicine.medical_specialty medicine.medical_treatment Logistic regression Pediatrics RJ1-570 Internal medicine medicine Sore throat Humans Prospective Studies Prospective cohort study Child Mechanical ventilation business.industry Delivery of Health Care Integrated SARS-CoV-2 Medical record Research COVID-19 medicine.disease Systemic Inflammatory Response Syndrome Systemic inflammatory response syndrome Hospitalization El Niño Pediatrics Perinatology and Child Health Vomiting medicine.symptom business |
| Zdroj: | BMC Pediatrics BMC Pediatrics, Vol 21, Iss 1, Pp 1-9 (2021) |
| ISSN: | 1471-2431 |
| Popis: | Background The spectrum of illness and predictors of severity among children with SARS-CoV-2 infection are incompletely understood. Methods Active surveillance was performed for SARS-CoV-2 by polymerase chain reaction among symptomatic pediatric patients in a quaternary care academic hospital laboratory beginning March 12, 2020. We obtained sociodemographic and clinical data 5 (+/-3) and 30 days after diagnosis via phone follow-up and medical record review. Logistic regression was used to assess predictors of hospitalization. Results The first 1000 symptomatic pediatric patients were diagnosed in our institution between March 13, 2020 and September 28, 2020. Cough (52 %), headache (43 %), and sore throat (36 %) were the most common symptoms. Forty-one (4 %) were hospitalized; 8 required ICU admission, and 2 required mechanical ventilation ( Conclusions In 1000 pediatric patients with systematic follow-up, most SARS-CoV-2 infections were mild, brief, and rarely required hospitalization. Pediatric predictors of hospitalization included comorbid conditions, Black race, Hispanic ethnicity, dyspnea and vomiting and were distinct from those reported among adults. |
| Databáze: | OpenAIRE |
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