First detection of enterovirus 71 from an acute flaccid paralysis case with residual paralysis in Iran

Autor:	Mohammad Mehdi Gouya, Abolreza Esteghamati, Mohsen Zahraie, Kobra Farrokhi, Hamideh Tabatabaie, Zahra Mehrabi, Zahra Shokati, Mohammad Reza Eshraghian, Katayoon Samimi Rad, Maryam Yousefi, Shohreh Shahmahmoodi, Taha Moosavi, Talat Mokhtari Azad, Rakhshandeh Nategh
Rok vydání:	2008
Předmět:	Acute flaccid paralysis Pediatrics medicine.medical_specialty Pathology Adolescent Neurological disorder Iran medicine.disease_cause Central nervous system disease Virology Enterovirus Infections Paralysis Enterovirus 71 Humans Medicine biology Foot-and-mouth disease Reverse Transcriptase Polymerase Chain Reaction business.industry virus diseases Sequence Analysis DNA medicine.disease biology.organism_classification Enterovirus A Human Infectious Diseases Muscle Hypotonia RNA Viral Enterovirus Female Viral disease medicine.symptom business
Zdroj:	Journal of Clinical Virology. 42:409-411
ISSN:	1386-6532
Popis:	In an attempt to determine the types of non-polio enteroviruses (NPEVs) in acute flaccid paralysis (AFP) cases in Iran, we detected enterovirus 71 (EV71) in an AFP case with residual paralysis for the first time. Cell culture detected no enteroviruses, while RT-PCR and subsequent sequencing revealed that the specimen was positive for EV71. EV71 is the causative agent of a variety of diseases from hand, foot and mouth disease to severe neurological complications and is now considered as an important cause of childhood acute flaccid paralysis.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13e54b38a645d40bb0092cf097f87aad https://doi.org/10.1016/j.jcv.2008.02.013 Zobrazit plný text záznamu Full Text from ScienceDirect