Global health-related quality of life in schizophrenia: systematic review and meta-analysis
Autor: | Farnaz Aghajani, Ahmad Ghashghaee, Sepideh Rezaei, Hossein Hosseinifard, Sima Rafiei, Afsaneh Dehnad, Samira Raoofi, Zahra Golmohammadi, Hosein Shabaninejad, Niloofar Ahmadi, Saba Ahmadi, Hamide Shabani, Sepideh Aghalou, Zahra Hoseinipalangi, Fatemeh Pashazadeh Kan |
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Rok vydání: | 2021 |
Předmět: |
Descriptive statistics
Oncology (nursing) business.industry Schizophrenia (object-oriented programming) Medicine (miscellaneous) Signs and symptoms General Medicine Disease Europe 03 medical and health sciences Medical–Surgical Nursing 0302 clinical medicine Systematic review Quality of life Meta-analysis Global health Quality of Life Schizophrenia Medicine Humans 030212 general & internal medicine business 030217 neurology & neurosurgery Clinical psychology |
Zdroj: | BMJ supportivepalliative care. 12(2) |
ISSN: | 2045-4368 |
Popis: | Background and aimSigns and symptoms of schizophrenia may have serious impacts on patients’ quality of life leading to concern about different aspects of their lives. This study presents a systematic review and meta-analysis of the studies examining the quality of life among patients with schizophrenia and its relationship with patients’ characteristics.Materials and methodsA total of 40 studies were extracted from searching of relevant databases published between 2000 and 2020. Descriptive data and correlation coefficients between patient’s characteristics and quality of life were extracted and the results were reported according to Preferred Reporting Items for Systematic Reviews and Meta-analyses standards and meta-analysis of pooled studies.ResultsIn total, 8363 patients with schizophrenia participated in 40 studies which used Schizophrenia Quality of Life Scale revision 4. The total score of quality of life (QOL) in the study subjects was reported to be 40.66. Weighted effect size analyses revealed a significant relationship between QOL and variables including patients’ age and duration of the disease. Furthermore, the highest (the worst) score of QOL in schizophrenia patients was observed in Europe 47.04 (95% CI 41.26 to 52.82) and the Euro region 47.05 (95% CI 41.18 to 52.92).ConclusionOverall, the QOL among patients with schizophrenia was in a good status, which could be improved through considering different life aspects of people living in various contexts. In fact, clarifying the determinants of QOL would be a key step in the provision of future treatment efforts. |
Databáze: | OpenAIRE |
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