Patient-specific online dose verification based on transmission detector measurements
| Autor: | Frank Lohr, Hansjoerg Wertz, Yuvaraj Sekar, Jens Fleckenstein, Johannes Thoelking, Ramesh Boggula, Frederik Wenz |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Quality Assurance
Health Care Computer science Linear particle accelerator 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Neoplasms Humans Dosimetry Radiology Nuclear Medicine and imaging Radiometry Radiation treatment planning business.industry Radiotherapy Planning Computer-Assisted Detector Radiotherapy Dosage Hematology Patient specific Oncology Transmission (telecommunications) Gamma Rays 030220 oncology & carcinogenesis Dose verification Radiotherapy Intensity-Modulated Particle Accelerators business Nuclear medicine Quality assurance |
| Popis: | Since IMRT-techniques lead to an increasingly complicated environment, a patient specific IMRT-plan verification is recommended. Furthermore, verifications during patient irradiation and 3D dose reconstruction have the potential to improve treatment delivery, accuracy and safety. This study provides a detailed investigation of the new transmission detector (DTD) Dolphin (IBA Dosimetry, Germany) for online dosimetry.The clinical performance of the DTD was tested by dosimetric plan verification in 2D and 3D for 18 IMRT-sequences. In 2D, DTD measurements were compared to a pre-treatment verification method and a treatment planning system by gamma index and dose difference evaluations. In 3D, dose-volume-histogram (DVH) indices and gamma analysis were evaluated. Furthermore, the error detection ability was tested with leaf position uncertainties and deviations in the linear accelerator (LINAC) output.The DTD measurements were in excellent agreement to reference measurements in both 2D (γ3%,3mm=(99.7±0.6)%1, ΔD±5%=(99.5±0.5)%) and 3D. Only a small dose underestimation (2%) within the target volume was observed when analyzing DVH-indices. Positional errors of the leaf banks larger than 1mm and errors in LINAC output larger than 2% were identified with the DTD.The DTD measures the delivered dose with sufficient accuracy and is therefore suitable for clinical routine. |
| Databáze: | OpenAIRE |
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