Activation of deoxycholate solubilized adenosine triphosphatase by ganglioside and asialoganglioside preparations
| Autor: | Beatriz L. Caputto, Alicia H.R. Maccioni, Ranwel Caputto |
|---|---|
| Rok vydání: | 1977 |
| Předmět: |
Ammonium sulfate
Ceramide ATPase Biophysics Lipidoses Biochemistry Asialoganglioside chemistry.chemical_compound Species Specificity Gangliosides Animals Magnesium Molecular Biology Adenosine Triphosphatases Ganglioside biology Sodium Brain Cell Biology Rats Enzyme Activation carbohydrates (lipids) Kinetics EGTA chemistry Solubilization Potassium Sialic Acids biology.protein Microsome Calcium Deoxycholic Acid |
| Zdroj: | Biochemical and Biophysical Research Communications. 74:1046-1052 |
| ISSN: | 0006-291X |
| DOI: | 10.1016/0006-291x(77)91623-0 |
| Popis: | ATPase was prepared from brain microsomes by solubilization with sodium deoxycholate and fractionated at different concentrations of ammonium sulfate. The Mg 2+ -ATPase was activated by total brain gangliosides, disialoganglioside, monosialo — ganglioside, hematoside, total brain gangliosides obtained from a patient with Tay-Sachs disease and asialoganglioside. The effect was smaller on Ca 2+ -ATPase and negligible on (Na + + K + )-ATPase. Lactosyl-ceramide, glucosyl-ceramide, galactosyl-ceramide, ceramide and sialyl-lactose failed to produce activation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|