An approach to novel fused triazole or tetrazole derivatives starting from benzimidazo[1,2‐ a ]quinazoline‐5(7 H )‐one and 5,7‐dihydro‐5‐oxopyrido[3′,2′:5,6]pyrimido[1,2‐ a ]benzimidazole

Autor:	Federico Da Settimo, Giampaolo Primofiore, Francesca Simorini, Antonio Da Settimo, Anna Maria Marini, Gianluca Pardi
Rok vydání:	2002
Předmět:	chemistry.chemical_compound Benzimidazole chemistry Stereochemistry Organic Chemistry Triazole Quinazoline Thio Tetrazole General Medicine Medicinal chemistry Dimroth rearrangement
Zdroj:	Scopus-Elsevier ResearcherID
ISSN:	1943-5193 0022-152X
DOI:	10.1002/jhet.5570390523
Popis:	The synthetic potential of the title compounds benzimidazo[1,2-a]quinazoline-5(7H)-one 2a and 5,7-dihydro-5-oxopyrido[3′,2′:5,6]pyrimido[1,2-a]benzimidazole 2b for the construction of novel polyhetero-cyclic frameworks is reported. Compounds 2a,b, by conversion into their thio analogues 3a,b, were used for the synthesis of tetrazole (5a,b) and triazole (7a,b) derivatives, as well as for an unexpected synthesis of tri-azoles 8a,b, isomers of 7a,b, resulting from the occurrence of a Dimroth rearrangement.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13cae395ef785147cbbf2db0b9caeeea https://doi.org/10.1002/jhet.5570390523 Zobrazit plný text záznamu Plný text