Diastereoselective synthesis of α-(aminomethyl)-γ-butyrolactones via a catalyst-free aminolactonization

Autor:	P. Veeraraghavan Ramachandran, Daniel R. Nicponski
Rok vydání:	2014
Předmět:	Proton Chemistry Metals and Alloys Stereoisomerism General Chemistry Deuterium Combinatorial chemistry Catalysis Surfaces Coatings and Films Electronic Optical and Magnetic Materials Cascade reaction 4-Butyrolactone Materials Chemistry Ceramics and Composites Solvents Organic chemistry
Zdroj:	Chemical communications (Cambridge, England). 50(96)
ISSN:	1364-548X
Popis:	An auto-catalytic domino reaction, presumably involving an aza-Michael reaction, proton transfer, and lactonization, furnishing α-(aminomethyl)-γ-butyrolactones in near quantitative yields and excellent diastereoselectivity is described.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13c8d8c824a7a9938107826f52af7b73 https://pubmed.ncbi.nlm.nih.gov/25340310 Zobrazit plný text záznamu