Drug-related problems among hospitalized patients with COPD in mainland China
| Autor: | Hui Jun Qu, Shusen Sun, Yun Liao, Ling Li, Qin Li, Ming-Kung Yeh, Dan Lv |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Mainland China Drug China medicine.medical_specialty Drug-Related Side Effects and Adverse Reactions Exacerbation Hospitalized patients media_common.quotation_subject Psychological intervention Pharmaceutical Science Pharmacy Pharmacists Toxicology Pulmonary Disease Chronic Obstructive 03 medical and health sciences Professional Role 0302 clinical medicine Humans Medicine Pharmacology (medical) Prospective Studies 030212 general & internal medicine Aged media_common Aged 80 and over Pharmacology COPD business.industry Middle Aged medicine.disease Hospitalization Pharmaceutical care 030228 respiratory system Emergency medicine Female Pharmacy Service Hospital business |
| Zdroj: | International Journal of Clinical Pharmacy. 41:1507-1515 |
| ISSN: | 2210-7711 2210-7703 |
| Popis: | BackgroundData are lacking about the extent of drug-related problems in hospitalized patients with COPD in China.ObjectiveIdentify types and causes of drug-related problems and assess interventions performed by pharmacists.SettingStudy was conducted in an academic teaching hospital in Shanghai, China.MethodBetween June 2017 and July 2018, 393 patients admitted to hospital for acute exacerbation of COPD hospitalized were enrolled. Patient demographics and clinical characteristics were collected. The drug-related problems and interventions were recorded and analyzed based on the Pharmaceutical Care Network Europe (PCNE)-DRP V 8.02 classification.Main outcome measuresThe number, types, causes, interventions, and outcomes of the problems were analyzed.ResultsA total of 640 DRPs, with 763 corresponding causes, were identified for 393 patients. “Treatment safety P2” was the most common type of problem (54.2%; 347/640), and the most common causes were “drug selection C1” (24.2%; 185/763), “dose selection C3” (21.5%; 164/763) and “treatment duration C4” (17.7%; 135/763). Antibiotics, corticosteroids, and proton pump inhibitors were the three primary medication classes associated with DRPs. Patients, hospitalized for more than eight days, taking ten or more drugs or having renal dysfunctions were more likely to have drug-related problems. Pharmacists totally proposed 1557 interventions to address the problems. Most interventions (91.0%; 1418/1557) were accepted, and 91.6% of the problems were solved.ConclusionThe prevalence of drug-related problems among the studied COPD patients was high. Pharmacists can have an important role in addressing the problems and optimizing the safety and effectiveness of therapies for hospitalized COPD patients. |
| Databáze: | OpenAIRE |
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