Predicting factors of present hepatitis C virus infection among patients positive for the hepatitis C virus antibody
| Autor: | Dong-Hee Kim, Jun Uk Lim, Jung Won Jeon, Joung Il Lee, Kwang Ro Joo, Chi Hoon Lee, Hyun Phil Shin, Jae Myung Cha, Hyun Jun Joung, Sung Wook Kang, Joon Ki Min |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male Hepacivirus Hepatitis C virus Hepatitis C virus Antibody medicine.disease_cause Immunoenzyme Techniques Predictive Value of Tests Diagnosis medicine Odds Ratio Humans lcsh:RC799-869 Molecular Biology Serum Albumin Aged Immunoassay Hepatology biology medicine.diagnostic_test Platelet Count virus diseases Alanine Transaminase Bilirubin Hepatitis C Odds ratio Hepatitis C Antibodies Middle Aged biology.organism_classification medicine.disease Virology digestive system diseases Alanine transaminase Immunology biology.protein RNA Viral lcsh:Diseases of the digestive system. Gastroenterology Original Article Female Antibody |
| Zdroj: | Clinical and molecular hepatology Clinical and Molecular Hepatology, Vol 19, Iss 4, Pp 376-381 (2013) |
| ISSN: | 2287-285X 2287-2728 |
| Popis: | Background/Aims To identify the predicting factors of present hepatitis C virus (HCV) infection among patients with positivity for antibodies to HCV (anti-HCV). Methods We analyzed patients who showed positive enzyme immunoassay (EIA) results and performed an HCV RNA test as a confirmatory test at Kyung Hee University Hospital at Gangdong from June 2006 to July 2012. The features distinguishing the groups with positive and negative HCV RNA results were reviewed. Results In total, 490 patients were included. The results of the HCV RNA test were positive and negative in 228 and 262 patients, respectively. The index value of anti-HCV, mean age, platelet counts, total bilirubin, prothrombin time international normalized ratio, albumin and alanine transaminase (ALT) levels differed significantly between the two groups. On multivariable analysis, an index value of anti-HCV >10 [odds ratio (OR)=397.27, P40 IU/L (OR=3.64, P=0.001), and albumin |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|