Electroanalytical determination of metronidazole in tablet dosage form

Autor: Murat Sadikoglu, Kamran Polat, Sultan Yagmur, Esra Baltaoglu, Gulsen Saglikoglu, Selehattin Yilmaz
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: Journal of the Serbian Chemical Society, Vol 78, Iss 2, Pp 295-302 (2013)
Popis: WOS:000315607000013 In this study, the electrochemical reduction and determination of metronidazole were easily realized in Britton-Robinson buffer (pH 4.01) using an UTGE by cyclic voltammetric (CV) and differential pulse voltammetric (DPV) techniques. In this acidic medium, one irreversible and a sharp cathodic peak were observed. A linear calibration curve for DPV analysis was constructed in the metronidazole concentration range 3 x10(-6)-9x10(-5) mol L-1. The limit of detection (LOD) and limit of quantification (LOQ) were 1.42x10(-7) and 4.76x10(-7) mol L-1 respectively.
Databáze: OpenAIRE