Microfluidic Crystallization of Surfactant-Free Doped Zinc Sulfide Nanoparticles for Optical Bioimaging Applications
| Autor: | Xiaohui Huang, Denis Badocco, Adolfo Speghini, Michele Maggini, Paolo Dolcet, Andrea Faresin, Francesca Tajoli, Silvia Gross, Jan-Dierk Grunwaldt, Tommaso Carofiglio, Nicola Dengo, Giacomo Lucchini, Maddalena Mognato, Christian Kübel |
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| Rok vydání: | 2020 |
| Předmět: |
Technology
Materials science Luminescence Surfactant free Surface Properties Microfluidics microfluidics Nanoparticle 02 engineering and technology doping NIR emission Sulfides 010402 general chemistry 01 natural sciences law.invention Ion chemistry.chemical_compound law Transition Elements Tumor Cells Cultured Humans General Materials Science Crystallization Particle Size optical bioimaging Doping Optical Imaging Microfluidic Analytical Techniques 021001 nanoscience & nanotechnology Zinc sulfide 0104 chemical sciences X-Ray Absorption Spectroscopy zinc sulfide chemistry Chemical engineering ZnS 2020-024-029424 A549 Cells Zinc Compounds TEM Nanoparticles 0210 nano-technology ddc:600 Research Article |
| Zdroj: | ACS Applied Materials & Interfaces ACS applied materials & interfaces, 12 (39), 44074–44087 |
| ISSN: | 1944-8252 1944-8244 |
| Popis: | The room-temperature controlled crystallization of monodispersed ZnS nanoparticles (average size of 5 nm) doped with luminescent ions (such as Mn$^{2+}$, Eu$^{3+}$, Sm$^{3+}$, Nd$^{3+}$, and Yb$^{3+}$) was achieved via a microfluidic approach. The preparation did not require any stabilizing ligands or surfactants, minimizing potential sources of impurities. The synthesized nanomaterials were characterized from a structural (XRD and XAS at lanthanide L$_{3}$ edges), morphological (TEM), and compositional (XPS, ICP-MS) perspective, giving complementary information on the materials’ features. In view of potential applications in the field of optical bioimaging, the optical emission properties of the doped nanoparticles were assessed, and samples showed strong luminescent properties while being less affected by self-quenching mechanisms. Furthermore, in vitro cytotoxicity experiments were conducted, showing no negative effects and evidencing the appeal of the synthesized materials for potential applications in the field of optical bioimaging. |
| Databáze: | OpenAIRE |
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