Proficiency Testing in Immunohematology in Ontario, Canada, 1975–1977
| Autor: | Donald E. Wood, Betty E. E. Croucher, K.L. Burnie, S.C. Ezer, Dorothy C. H. Ley, Marie C. Quantz, James F. Murray, P.H. Pinkerton, John A. Mcbride, K.C. Carstairs |
|---|---|
| Rok vydání: | 1979 |
| Předmět: |
medicine.medical_specialty
ABO Blood-Group System Coombs test Isoantibodies ABO blood group system Proficiency testing Humans Medicine False Positive Reactions Typing False Negative Reactions Ontario Rh-Hr Blood-Group System medicine.diagnostic_test business.industry Obstetrics Continuing education General Medicine Coombs Test Blood Grouping and Crossmatching ABO typing Immunologic Techniques Laboratory Proficiency Testing Laboratories business Ontario canada |
| Zdroj: | American Journal of Clinical Pathology. 72:559-563 |
| ISSN: | 1943-7722 0002-9173 |
| DOI: | 10.1093/ajcp/72.4.559 |
| Popis: | Since April 1975 the proficiency of laboratories in Ontario that perform immunohematology tests has been assessed. While the majority of test samples have required only ABO and Rh(D) typing, others have posed problems. The error rate in uncomplicated ABO typing was 1.3/1,000 in 17,479 tests and that in straightforward Rh(D) grouping, 6.6/1,000 in 17,757 tests. False-negative (36/1,000) and false-positive (1.4/1,000) direct antiglobulin tests occurred. Errors in detection of strong autoantibodies ( e.g ., anti-D) were 19.7, 10.2 and 5.1/1,000 in three test samples. A2B or A2 cells with anti-A1 in serum were sent out in two surveys; error rates in ABO interpretation were 189 and 52/1,000, respectively. Laboratories also experienced difficulty in interpreting the Rh(D) type of cells with positive antiglobulin tests. These surveys have had several effects: (1) laboratories with poor performance have been identified, (2) patterns of practice have been influenced, (3) areas of ignorance have been identified, and (4) a stimulus has been provided for continuing education in immunohematology. |
| Databáze: | OpenAIRE |
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