Can abdominal multi-detector CT diagnose spinal osteoporosis?
| Autor: | Effie Petinellis, Antonios E. Papadakis, John Damilakis, G. Papadokostakis, Apostolos H. Karantanas |
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| Rok vydání: | 2007 |
| Předmět: |
musculoskeletal diseases
Radiography Abdominal medicine.medical_specialty Radiography Osteoporosis Sensitivity and Specificity Medicine Humans Radiology Nuclear Medicine and imaging cardiovascular diseases Osteoporosis Postmenopausal Neuroradiology Bone mineral Conversion equation Lumbar Vertebrae medicine.diagnostic_test business.industry Ultrasound Reproducibility of Results Interventional radiology General Medicine Middle Aged medicine.disease Multi detector ct body regions cardiovascular system Spinal Fractures Female Spinal Diseases Radiology business Nuclear medicine Tomography X-Ray Computed |
| Zdroj: | European radiology. 19(1) |
| ISSN: | 1432-1084 |
| Popis: | The aim of this study was to (1) generate quantitative CT (QCT) densitometric data based on routine abdominal multi-detector (MDCT) examinations and (2) investigate whether these data can be used to differentiate osteoporotic from healthy females. Twenty-five female patients (group A) with a history of radiotherapy were examined both with routine abdominal MDCT and standard QCT to generate a MDCT-to-QCT conversion equation. Twenty-one osteoporotic (group B) and 23 healthy female patients (group C) were also recruited in the study. Patients of groups B and C underwent routine abdominal MDCT examination for various clinical indications. Mean bone mineral density (BMD) in patients of group A was 103.4 mg/ml +/- 32.8 with routine abdominal MDCT and 91.0 mg/ml +/- 28.5 with QCT. Quantitative CT BMD(QCT) values for patients in groups B and C were calculated utilizing the BMD(MDCT) values derived from routine abdominal MDCT data sets and the MDCT to QCT conversion equation: BMD(QCT)=0:78 x BMD(MDCT) + 10:13. The calculated QCT densitometric data adequately differentiated osteoporotic from healthy females (area under ROC curve 0.828, p = 0.05). In conclusion, this study showed that in a group of female patients, QCT data derived from routine abdominal MDCT examinations discriminated osteoporotic from healthy subjects. |
| Databáze: | OpenAIRE |
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