TIPIC Syndrome: Beyond the Myth of Carotidynia, a New Distinct Unclassified Entity
| Autor: | N. Menjot de Champfleur, S. De Gaalon, M. Amor-Sahli, Fabrice Bonneville, Olivier Gout, Nathalie Nasr, Augustin Lecler, Jean-Philippe Cottier, Olivier Naggara, E. Auffray-Calvier, J. Bensoussan, Jean-Claude Sadik, H. Picard, G. Volle, Dragos Catalin Jianu, Frédérique Charbonneau, Julien Savatovsky, B. Carsin, M. Obadia, Arthur Varoquaux, C. Calazel |
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| Přispěvatelé: | Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier), Laboratoire Charles Coulomb (L2C), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Centre de résonance magnétique biologique et médicale (CRMBM), Aix Marseille Université (AMU)-Assistance Publique - Hôpitaux de Marseille (APHM)-Centre National de la Recherche Scientifique (CNRS), Assistance Publique - Hôpitaux de Marseille (APHM)-Aix Marseille Université (AMU)-Centre National de la Recherche Scientifique (CNRS), Hôpital de la Conception [CHU - APHM] (LA CONCEPTION) |
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
Adult Carotid Artery Diseases Vasculitis Central Nervous System medicine.medical_specialty [SDV]Life Sciences [q-bio] Carotidynia Magnetic resonance angiography 030218 nuclear medicine & medical imaging Diagnosis Differential 03 medical and health sciences 0302 clinical medicine Text mining Diagnosis medicine Humans Radiology Nuclear Medicine and imaging Vasculitis Central Nervous System Tomography Retrospective Studies Observer Variation Neck pain Neck Pain medicine.diagnostic_test business.industry Retrospective cohort study Syndrome Middle Aged medicine.disease 3. Good health Surgery Cerebral Angiography X-Ray Computed Differential Female Neurology (clinical) Differential diagnosis medicine.symptom Nervous System Diseases business Tomography X-Ray Computed 030217 neurology & neurosurgery Magnetic Resonance Angiography Cerebral angiography Follow-Up Studies |
| Zdroj: | American Journal of Neuroradiology American Journal of Neuroradiology, American Society of Neuroradiology, 2017, 38 (7), pp.1391--1398. ⟨10.3174/ajnr.A5214⟩ |
| ISSN: | 0195-6108 |
| DOI: | 10.3174/ajnr.A5214⟩ |
| Popis: | BACKGROUND AND PURPOSE: The differential diagnosis of acute cervical pain includes nonvascular and vascular causes such as carotid dissection, carotid occlusion, or vasculitis. However, some patients present with unclassified vascular and perivascular changes on imaging previously reported as carotidynia. The aim of our study was to improve the description of this as yet unclassified clinico-radiologic entity. MATERIALS AND METHODS: From January 2009 through April 2016, 47 patients from 10 centers presenting with acute neck pain or tenderness and at least 1 cervical image showing unclassified carotid abnormalities were included. We conducted a systematic, retrospective study of their medical charts and diagnostic and follow-up imaging. Two neuroradiologists independently analyzed the blinded image datasets. RESULTS: The median patient age was 48 years. All patients presented with acute neck pain, and 8 presented with transient neurologic symptoms. Imaging showed an eccentric pericarotidian infiltration in all patients. An intimal soft plaque was noted in 16 patients, and a mild luminal narrowing was noted in 16 patients. Interreader reproducibility was excellent. All patients had complete pain resolution within a median of 13 days. At 3-month follow-up, imaging showed complete disappearance of vascular abnormalities in 8 patients, and a marked decrease in all others. CONCLUSIONS: Our study improved the description of an unclassified, clinico-radiologic entity, which could be described by the proposed acronym: TransIent Perivascular Inflammation of the Carotid artery (TIPIC) syndrome. |
| Databáze: | OpenAIRE |
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