A Novel Methicillin-Resistant Staphylococcus aureus t11469 and a Poultry Endemic Strain t002 (ST5) Are Present in Chicken in Ebonyi State, Nigeria
Autor: | Simon I. Okekpa, Azi Simon Onyema, Blake M. Hanson, Lynda C. Nwadi, G.A. Ibiam, Josiah Ademola Onaolapo, Chinwe Ezeruigbo, Busayo Olalekan Olayinka, B. N. Ukwah, Michael O. Elom, Victor U. Usanga, Amos Nworie, Joseph O. Ehinmidu, Shylo E. Wardyn, Nse O. Umoh, Tara C. Smith |
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Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
Methicillin-Resistant Staphylococcus aureus
0301 basic medicine Veterinary medicine Article Subject Virulence Factors medicine.drug_class 030106 microbiology Antibiotics Nigeria lcsh:Medicine Drug resistance Biology medicine.disease_cause General Biochemistry Genetics and Molecular Biology Microbiology 03 medical and health sciences Cloaca Drug Resistance Bacterial medicine Animals Pathogen Poultry Diseases Molecular Epidemiology General Immunology and Microbiology Molecular epidemiology business.industry lcsh:R General Medicine Staphylococcal Infections Methicillin-resistant Staphylococcus aureus Anti-Bacterial Agents Molecular Typing Staphylococcus aureus Vancomycin Livestock Nasal Cavity business Chickens Research Article medicine.drug |
Zdroj: | BioMed Research International, Vol 2017 (2017) BioMed Research International |
ISSN: | 2314-6133 |
DOI: | 10.1155/2017/2936461 |
Popis: | Background. The changing epidemiology of methicillin-resistantStaphylococcus aureus(MRSA) from a hospital-associated pathogen to an organism commonly found in the community and in livestock reflects an organism well-equipped to survive in diverse environments and adjust to different environmental conditions including antimicrobial use.Methods. We investigated the molecular epidemiology ofS. aureusand MRSA in poultry in Ebonyi State, Nigeria. Samples were collected from 1800 birds on 9 different farms within the state. Positive isolates were tested for antibiotic susceptibility and molecular typing.Results. Prevalence in birds was 13.7% (247/1800). MRSA prevalence in poultry was 0.8%. The prevalence of MRSA in broilers and layers was 1.2% and 0.4%, respectively. All tested isolates were susceptible to vancomycin. Molecular analysis of the isolates revealed 3spatypes: t002, t084, and a novelspatype, t11469. The novelspatype t11469 belonged to sequence type ST5.Conclusion. The detection of t002 in chicken suggests the presence of livestock-associated MRSA in poultry in Ebonyi State. The detection of the newspatype t11469 in poultry that has not been characterised to ascertain its pathogenic potential remains a cause for concern, especially as some were found to carry PVL genes, a putative virulence factor in staphylococcal infection. |
Databáze: | OpenAIRE |
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