Long-term serological follow-up after primary Coxiella burnetii infection in patients with vascular risk factors for chronic Q fever
| Autor: | Sheila B. Buijs, Sanne K. Stuart, André S. van Petersen, Peter C. Wever, Jan Jelrik Oosterheert, Chantal P. Bleeker-Rovers, Andy I. M. Hoepelman, Nicole H. M. Renders, Olivier H.J. Koning, Steffi Karhof |
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| Rok vydání: | 2021 |
| Předmět: |
Microbiology (medical)
Male medicine.medical_specialty Blood vessel prosthesis Q fever Serology Medical microbiology Informed consent Risk Factors Internal medicine medicine Humans In patient Aged Retrospective Studies biology business.industry Brief Report General Medicine Middle Aged medicine.disease Coxiella burnetii biology.organism_classification Aneurysm Antibodies Bacterial Titer Infectious Diseases lnfectious Diseases and Global Health Radboud Institute for Health Sciences [Radboudumc 4] Immunoglobulin G Female business Q Fever |
| Zdroj: | European Journal of Clinical Microbiology and Infectious Diseases, 40, 7, pp. 1569-1572 European Journal of Clinical Microbiology & Infectious Diseases European Journal of Clinical Microbiology and Infectious Diseases, 40, 1569-1572 |
| ISSN: | 0934-9723 |
| Popis: | We evaluated the long-term serological follow-up of patients with vascular risk factors for chronic Q fever that were previously Coxiellaburnetii seropositive. C. burnetii phase I IgG titers were reevaluated in patients that gave informed consent or retrospectively collected in patients already deceased or lost to follow-up. Of 107 patients, 25 (23.4%) became seronegative, 77 (72.0%) retained a profile of past resolved Q fever infection, and five (4.7%) developed chronic Q fever. We urge clinicians to stay vigilant for chronic Q fever beyond two years after primary infection and perform serological testing based on clinical presentation. |
| Databáze: | OpenAIRE |
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