Hyperglycemia in pregnancy: sleep alterations, comorbidities and pharmacotherapy
| Autor: | Cristina Façanha, Veralice de Bruin, Pedro de Bruin, Arthur Façanha, Hellen Cristina Rocha, Mariana Araujo, Adriana Forti, Rejane Macêdo |
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| Rok vydání: | 2021 |
| Předmět: |
Sleep Wake Disorders
Diabetes mellitus. Sleep. Pregnancy in diabetics. Diabetes Medicine (General) medicine.medical_specialty endocrine system diseases Excessive daytime sleepiness Disorders of Excessive Somnolence 030204 cardiovascular system & hematology Pittsburgh Sleep Quality Index 03 medical and health sciences R5-920 0302 clinical medicine Pregnancy Internal medicine Diabetes mellitus medicine Humans 030212 general & internal medicine Type 1 diabetes business.industry Epworth Sleepiness Scale Type 2 Diabetes Mellitus General Medicine medicine.disease Sleep in non-human animals Gestational diabetes Diabetes Gestational Diabetes Mellitus Type 2 Hyperglycemia gestational. Sleepiness Female medicine.symptom Sleep business |
| Zdroj: | Revista da Associação Médica Brasileira v.67 n.1 2021 Revista da Associação Médica Brasileira Associação Médica Brasileira (AMB) instacron:AMB Revista da Associação Médica Brasileira, Volume: 67, Issue: 1, Pages: 45-51, Published: 31 MAY 2021 Revista da Associação Médica Brasileira, Vol 67, Iss 1, Pp 45-51 (2021) |
| ISSN: | 1806-9282 0104-4230 |
| DOI: | 10.1590/1806-9282.67.01.20200216 |
| Popis: | SUMMARY OBJECTIVE: To investigate sleep alterations and associated factors in pregnant diabetic women (n=141). METHODS: Sleep profile, sociodemographics and clinical information were collected. Poor sleep quality (Pittsburgh Sleep Quality Index >5) and excessive daytime sleepiness (Epworth Sleepiness Scale ≥10), sleep duration (h), sleep latency (min), frequent sleep interruption and short sleep (≤6 h) were assessed in type 1 diabetes mellitus (16.3%), type 2 diabetes mellitus (25.5%) and gestational diabetes mellitus (58.2%). RESULTS: Poor sleep quality was found in 58.8% of patients and daytime sleepiness in 25.7%, regardless of hyperglycemia etiology. No correlation existed between daytime sleepiness and poor sleep quality (Pearson correlation r=0.02, p=0.84). Short sleep duration occurred in 1/3 of patients (31.2%). Sleep interruptions due to frequent urination affected 72% of all and sleep interruptions due to any cause 71.2%. Metformin was used by 65.7% of type 2 diabetes mellitus and 28.7% of gestational diabetes mellitus. In gestational diabetes mellitus, parity number was independently associated with poor sleep quality (p=0.02; OR=1.90; 95%CI 1.07-3.36) and metformin use was also independently associated with poor sleep quality (p=0.03; OR=2.36; 95%CI 1.05-5.29). CONCLUSIONS: Our study originally shows that poor sleep quality and excessive daytime sleepiness are frequent in diabetic pregnancy due to different etiologies. Interestingly, only in gestational diabetes mellitus, metformin therapy and higher parity were associated with poor sleep quality. |
| Databáze: | OpenAIRE |
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