Life expectancy of patients undergoing surgical aortic valve replacement compared with that of the general population
| Autor: | Daniel Hernández-Vaquero, Marcel Almendarez, César Morís, Isaac Pascual, Rocío Díaz, Alberto Alperi, Pablo Avanzas, Hector Cubero-Gallego, Alain Escalera |
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| Rok vydání: | 2019 |
| Předmět: |
Male
Pulmonary and Respiratory Medicine medicine.medical_specialty Population 030204 cardiovascular system & hematology Rate ratio Transcatheter Aortic Valve Replacement 03 medical and health sciences Life Expectancy 0302 clinical medicine Aortic valve replacement medicine Humans 030212 general & internal medicine education Survival rate Survival analysis Aged Proportional Hazards Models education.field_of_study business.industry Hazard ratio Aortic Valve Stenosis medicine.disease Confidence interval Surgery Survival Rate Stenosis Treatment Outcome Spain Aortic Valve Heart Valve Prosthesis Female Cardiology and Cardiovascular Medicine business |
| Zdroj: | Interactive CardioVascular and Thoracic Surgery. 30:394-399 |
| ISSN: | 1569-9285 |
| DOI: | 10.1093/icvts/ivz268 |
| Popis: | OBJECTIVES Surgical aortic valve replacement (SAVR) changes the natural history of severe aortic stenosis. However, whether the life expectancy of patients with severe aortic stenosis undergoing this surgical procedure is fully restored is unknown. The objective of this study was to assess if the life expectancy of patients aged >75 years is fully restored after undergoing surgery for severe aortic stenosis. METHODS We compared long-term survival of a group of patients aged >75 years, who underwent SAVR at our institution with the long-term survival of the general population. We matched each patient with 100 simulated individuals (control group) of the same age, sex and geographical region who died as indicated by the National Institute of Statistics. We compared survival curves and calculated hazard ratio (HR) or incidence rate ratio. Statistical significance existed if confidence intervals (CIs) did not overlap or did not include the value 1, as appropriate. RESULTS Average life expectancy of surgical patients who survived the postoperative period was 90.91 months (95% CI 82.99–97.22), compared to 92.94 months (95% CI 92.39–93.55) in the control group. One-, 5- and 8-year survival rates for SAVR patients who were discharged from the hospital were 94.9% (95% CI 92.74–96.43%), 71.66% (95% CI 67.37–75.5%) and 44.48% (95% CI 38.14–50.61%), respectively, compared to that of the general population: 95.8% (95% CI 95.64–95.95%), 70.64% (95% CI 70.28%–71%) and 47.91% (95% CI 47.52–48.31%), respectively (HR 1.07, 95% CI 0.94–1.22). CONCLUSION For patients over the age of 75 years who underwent SAVR and survived the postoperative period, life expectancy and survival rates were similar to that of the general population. |
| Databáze: | OpenAIRE |
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