Multilobulated 'flower' cells in a subcutaneous mass aspirate from a cat
| Autor: | F. Simon, C. Hopfner, D. Musch, O. Dela Fontaine, K. P. Freeman, M. Seroka, D. Fritz, M. Rabeyrin |
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| Rok vydání: | 2005 |
| Předmět: |
Male
Pathology medicine.medical_specialty Lymphoma B-Cell Myeloid Biology Cat Diseases Subcutaneous Tissue Cytology Jugular vein Immunochemistry Ascites medicine Animals Vimentin Cell Nucleus General Veterinary Anatomy medicine.disease CD79A Immunohistochemistry Staining Lymphoma medicine.anatomical_structure Cats Jugular Veins medicine.symptom CD79 Antigens |
| Zdroj: | Veterinary Clinical Pathology. 34:429-433 |
| ISSN: | 0275-6382 |
| DOI: | 10.1111/j.1939-165x.2005.tb00076.x |
| Popis: | An 8-year-old intact male cat was presented with a subcutaneous mass in the region of the right jugular vein. Cytologic and histopathologic examinations revealed cells with multilobulated nuclei (flower cells). Immunochemistry using a panel of markers showed vimentin-positivity on cytologic specimens, and postive staining for CD79a and BLA36 on histologic specimens. The final diagnosis was lymphoma of B-cell origin. We have observed similar multilobulated cells in ascites fluid, thoracic fluid, and peripheral blood from dogs and cats with a variety of lymphoid and myeloid neoplasms. Cells with multilobulated nuclei that resemble flower petals also have been described in humans. These cells are infrequently observed in canine and feline cytology specimens and require immunochemistry to determine their cell of origin. |
| Databáze: | OpenAIRE |
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