Regional cerebral blood flow in chronic alcoholics measured by single photon emission computerized tomography
| Autor: | Henrik Toft Sørensen, Olaf B. Paulson, B. Melgaard, P. Ahlgren, L. Henriksen, Ulla Tarp Danielsen |
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| Rok vydání: | 2009 |
| Předmět: |
Adult
Male Intelligence Computed tomography Single photon emission computerized tomography Random Allocation medicine Humans In patient Aged Neurologic Examination Tomography Emission-Computed Single-Photon Cerebral atrophy Psychological Tests Ethanol medicine.diagnostic_test Intellectual impairment business.industry Brain Chronic alcoholic General Medicine Blood flow Middle Aged medicine.disease Alcoholism Neurology Cerebral blood flow Cerebrovascular Circulation Neurology (clinical) Atrophy Tomography X-Ray Computed Nuclear medicine business Blood Flow Velocity Xenon Radioisotopes |
| Zdroj: | Acta Neurologica Scandinavica. 82:87-93 |
| ISSN: | 1600-0404 0001-6314 |
| DOI: | 10.1111/j.1600-0404.1990.tb01594.x |
| Popis: | Regional cerebral blood flow (CBF) was measured by single photon emission computerized tomography of inhaled 133-Xe in 20 chronic alcoholic men. Mean CBF was 51 ml/(100 g x min) compared with 53 ml/(100 g x min) in 20 normals. Reduced cerebellar blood flow correlated both to structural abnormalities seen on CT scan and to cognitive dysfunction. Slight abnormalities of the regional CBF was observed in the alcoholics. They had a higher incidence of regional low flow areas than a control group. Low flow areas were found in frontal and posterior parts of the brain not only in patients with atrophia, but also in patients without CT abnormalities, suggesting neuronal dysfunction. The occurrence of regional low flow areas was associated with the severity of alcoholism, cerebral atrophy and intellectual impairment. |
| Databáze: | OpenAIRE |
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