The relationship of background mammographic pattern to hormone dependency in breast cancer
| Autor: | Roebuck Ej, Roger W. Blamey, C P Hinton, K. Griffiths, R. I. Nicholson, M. R. Williams, J. Glaves |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Oncology
medicine.medical_specialty medicine.drug_class Mammary gland Estrogen receptor Breast Neoplasms Breast cancer Internal medicine medicine Mammography Humans Breast Fibrocystic Breast Disease Gynecology medicine.diagnostic_test business.industry medicine.disease Hormones medicine.anatomical_structure Receptors Estrogen Estrogen Dysplasia Surgery Female Menopause business Breast carcinoma Hormone |
| Zdroj: | The British journal of surgery. 71(5) |
| ISSN: | 0007-1323 |
| Popis: | We have studied the relationship between mammographic parenchymal pattern of the breast and oestrogen receptor (ER) status in the primary tumour in 337 patients with operable invasive breast cancer, and the response to endocrine therapy in patients subsequently developing secondary disease. Patients with dysplastic (DY) parenchymal pattern are significantly more likely to develop tumours which are ER-positive. In 92 patients who subsequently developed secondary disease, those whose primary tumour arose in a DY pattern breast were significantly more likely to respond to endocrine therapy irrespective of their ER status. |
| Databáze: | OpenAIRE |
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