Pre-transplant treatment of hepatocellular carcinoma: assessment of tumor necrosis in explanted livers

Autor: Kathryn Tanaka, Steven Komura, Lansdale Lau, Linda L. Wong
Rok vydání: 2004
Předmět:
Zdroj: Clinical transplantation. 18(3)
ISSN: 0902-0063
Popis: Although liver transplantation (LT) is likely the most effective therapy for localized hepatocellular cancer (HCC), limited donor livers have resulted in prolonged waiting times for transplant. Pre-transplant therapy such as transarterial chemoembolization (TACE), percutaneous ethanol injection (PEI), and radiofrequency ablation (RFA) may be needed to sustain patients who are waiting. Records, imaging studies, and pathology to identify tumor necrosis on 15 explanted livers with HCC were reviewed. Forty-nine nodules were removed from 15 explanted livers. Five nodules in three livers that received no pre-transplant therapy were excluded from the study. Of the remaining 44 nodules in 12 patients, 29 (66%) had 75% or more tumor necrosis. Fifteen nodules in five patients had
Databáze: OpenAIRE
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