Endometriosis allergic or autoimmune disease: pathogenetic aspects - a case control study
| Autor: | Mossa B, Donatella Caserta, M. Moscarini, Maddalena Mallozzi, Fabio M. Pulcinelli |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
0301 basic medicine
Adult medicine.medical_specialty Allergy Endometriosis Antigen-Presenting Cells Comorbidity Autoimmune Diseases 03 medical and health sciences Young Adult 0302 clinical medicine Th2 Cells Hypersensitivity Prevalence Medicine Humans Young adult Asthma Retrospective Studies Autoimmune disease Immunity Cellular 030219 obstetrics & reproductive medicine Chi-Square Distribution business.industry Tumor Necrosis Factor-alpha Case-control study Obstetrics and Gynecology Retrospective cohort study Middle Aged Th1 Cells medicine.disease Dermatology Interleukin-12 Immunity Humoral Interleukin-10 030104 developmental biology Reproductive Medicine Italy Case-Control Studies Immunology Female business |
| Popis: | Purpose of investigation The aim of this study was to evaluate the correlation between endometriosis and pathologies on an immune basis for the possible involvement of the immune system in the pathogenesis of endometriosis. Materials and methods In this retrospective study, data of 304 patients with endometriosis and 318 without endometriosis were collected in a uniform manner for both groups and inserted into two databases, respectively, for patients with and without endometriosis. The authors calculated the percentages of patients with allergies, autoimmune diseases, asthma in both groups, and later statistical analysis were performed with two different chi-square tests. Results The results obtained have shown that patients with endometriosis have a higher prevalence of allergies (p = 0.0003) and coexistence of both allergies and autoimmune diseases (p = 0.0274), compared to those without. Conclusions The present study seems to support the possible association between endometriosis and allergic diseases. |
| Databáze: | OpenAIRE |
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