Preliminary assessment of captopril sonography in screening for renal artery stenosis
| Autor: | Eric B. Grossman, Nancy Carson, Victor N. Ghaed, Michael V.U. Azodo, Ronald H. Gottlieb, David L. Waldman, Graeme H. Watt, Jeffrey L. Lieberman, William B. Robinette |
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| Rok vydání: | 1996 |
| Předmět: |
Adult
Male medicine.medical_specialty Captopril Adolescent Urology Renal Artery Obstruction Angiotensin-Converting Enzyme Inhibitors Renal artery stenosis Kidney Renovascular hypertension medicine Humans Radiology Nuclear Medicine and imaging cardiovascular diseases Prospective Studies Prospective cohort study Child Radionuclide Imaging Aged Ultrasonography Aged 80 and over business.industry Middle Aged medicine.disease medicine.anatomical_structure Hypertension Renovascular Vascular resistance Technetium Tc 99m Pentetate Both kidneys Female Iodohippuric Acid Vascular Resistance Radiology business medicine.drug |
| Zdroj: | Academic radiology. 3(1) |
| ISSN: | 1076-6332 |
| Popis: | We assessed the usefulness of the resistive index (RI) and renal length in predicting a significant renal artery stenosis (RAS) and evaluated the effect of captopril on the RI in kidneys with and without a significant RAS.The RIs and renal lengths of both kidneys were measured in 39 patients who were referred for captopril renography for suspected renovascular hypertension. The difference in RIs (delta RI), the smaller RI (SRI), the difference in lengths (delta L), and the shorter length (SL) of the patient's two kidneys were determined. The accuracy of each of these parameters was calculated using captopril renography (n = 39) and arteriography (n = 9) as the gold standards.There was a significant difference in the delta RI (P.05), SRI (p.001), and delta L (p.05) in patients with a positive captopril renogram for a significant RAS. Captopril increased delta RI (p = .052) in patients with a positive captopril renogram (n = 6). Use of an SRI threshold of less than .55 resulted in ultrasound being as accurate as captopril renography in predicting an angiographically documented stenosis of greater than or equal to 50%.The RI and renal length are useful in detecting a significant RAS. In this preliminary study, captopril was shown to increase delta RI in patients with a significant RAS, but larger prospective studies are necessary to further assess the value of captopril sonography in detecting a significant RAS. |
| Databáze: | OpenAIRE |
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