Pattern of use and pharmacoeconomic impact of antihypertensive drugs in a north Indian referral hospital
| Autor: | R. S. Karan, Samir Malhotra, Sanjay Jain, Promila Pandhi |
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| Rok vydání: | 2001 |
| Předmět: |
Adult
Male medicine.medical_specialty Pediatrics Referral Combination therapy Adrenergic beta-Antagonists India Angiotensin-Converting Enzyme Inhibitors Drug Costs Pharmacoeconomics Epidemiology medicine Adverse Drug Reaction Reporting Systems Humans Pharmacology (medical) Medical prescription Hospitals Teaching Referral and Consultation Antihypertensive Agents Pharmacology business.industry Data Collection Medical record Public health General Medicine Middle Aged Calcium Channel Blockers medicine.disease Drug Utilization Hypertension Emergency medicine Female business Adverse drug reaction |
| Zdroj: | Scopus-Elsevier |
| ISSN: | 1432-1041 0031-6970 |
| DOI: | 10.1007/s002280100333 |
| Popis: | Objective: The current study was designed to investigate drug utilisation and the pharmacoeconomics of hypertension in the hypertension clinic of a tertiary-care hospital. Methods: The study was conducted in patients attending the hypertension clinic of Nehru Hospital, Postgraduate Institute of Medical Education and Research, Chandigarh, India. A survey of prescriptions was carried out, and the information obtained was further corroborated by seeing the medical records as well as patient interviews. Results: A total of 1076 prescriptions were evaluated. Beta-adrenoceptor-blocking agents (51%), calcium antagonists (47%) and angiotensin-converting enzyme inhibitors (46%) were the most popular drugs. The utilisation of thiazides was less than expected. Combination therapy was used more commonly than monotherapy (53.8% vs 46.7%). Oral hypoglycaemic agents and lipid-lowering agents were commonly co-prescribed along with antihypertensive medications. About 30% of drugs were prescribed by generic name and 90% were from the national essential drugs list. Of the per capita income, 10.6% was spent on the treatment of hypertension. The mean monthly cost of various drugs ranged between US $0.8 and US $6.6. A total of 91 adverse drug reaction (ADRs) were encountered in the study; the added cost of treatment of these ADRs was US $211. Conclusion: In general, the treatment guidelines for hypertension were followed in our hospital. The utilisation of thiazides was an area requiring improvement. The cost of treatment of hypertension was substantial and imparted a significant economic burden on the patients. |
| Databáze: | OpenAIRE |
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