Cytogenetic biodosimetry for radiation accidents in China
| Autor: | Yumin Lyu, Ping Wang, Yu Gao, Lin Han |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Oncology
lcsh:Medical physics. Medical radiology. Nuclear medicine medicine.medical_specialty Strategy and Management lcsh:R895-920 Ring chromosome Chromosomal translocation Nucleoplasmic bridges Industrial and Manufacturing Engineering Dicentric chromosome Cytogenetics Biodosimetry Internal medicine Dose estimation medicine Cytokinesis-block micronuclei business.industry Mechanical Engineering Chromosomal aberrations Premature condensation chromosome ring Metals and Alloys Clinical diagnosis Micronucleus test business Radiation Accidents |
| Zdroj: | Radiation Medicine and Protection, Vol 1, Iss 3, Pp 133-139 (2020) |
| ISSN: | 2666-5557 |
| Popis: | Cytogenetic indicators, especially dicentric chromosomes, have been globally considered the gold standard of biological dose estimation for more than 60 years. The application of these indicators to biological dose estimation in victims of radiation accidents in China has undergone approximately 40 years of development and thus provides more accurate information for the clinical diagnosis and patients’ treatment. This paper reviews the application and future development of cytogenetic indicators, including chromosomal aberrations (dicentric chromosomes and chromosomal translocations), cytokinesis-block micronuclei, nucleoplasmic bridges, and premature condensation chromosome ring, as biodosimeters in China. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|