Usefulness of core needle biopsy for the diagnosis of thyroid Burkitt’s lymphoma: a case report and review of the literature
Autor: | Gabriele Pozzato, Stella Bernardi, Veronica Calabrò, Deborah Bonazza, Bruno Fabris, Fabrizio Zanconati, Andrea Michelli |
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Přispěvatelé: | Bernardi, Stella, Michelli, Andrea, Bonazza, Deborah, Calabrò, Veronica, Zanconati, Fabrizio, Pozzato, Gabriele, Fabris, Bruno |
Jazyk: | angličtina |
Rok vydání: | 2018 |
Předmět: |
Thyroid nodules
medicine.medical_specialty endocrine system Burkitt’s lymphoma endocrine system diseases Thyroid lymphomas Endocrinology Diabetes and Metabolism medicine.medical_treatment Thyroid Gland 030209 endocrinology & metabolism Case Report lcsh:Diseases of the endocrine glands. Clinical endocrinology Case report Core needle biopsy Thyroid 03 medical and health sciences Endocrinology 0302 clinical medicine Cytology hemic and lymphatic diseases Thyroid lymphoma Biopsy Antineoplastic Combined Chemotherapy Protocols medicine Humans Thyroid Neoplasms Thyroid Nodule Chemotherapy lcsh:RC648-665 medicine.diagnostic_test business.industry Nodule (medicine) General Medicine Middle Aged medicine.disease Burkitt Lymphoma Lymphoma Diabetes and Metabolism medicine.anatomical_structure 030220 oncology & carcinogenesis Female Radiology Biopsy Large-Core Needle medicine.symptom business Burkitt's lymphoma |
Zdroj: | BMC Endocrine Disorders BMC Endocrine Disorders, Vol 18, Iss 1, Pp 1-7 (2018) |
ISSN: | 1472-6823 |
Popis: | Background Thyroid lymphomas are an exceptional finding in patients with thyroid nodules. Burkitt’s lymphoma is one of the rarest and most aggressive forms of thyroid lymphomas, and its prognosis depends on the earliness of medical treatment. Given the rarity of this disease, making a prompt diagnosis can be challenging. For instance, fine-needle aspiration (FNA) cytology, which is the first-line diagnostic test that is performed in patients with thyroid nodules, is often not diagnostic in cases of thyroid lymphomas, with subsequent delay of the start of therapy. Case presentation Here we report the case of a 52-year-old woman presenting with a rapidly enlarging thyroid mass. Thyroid ultrasonography demonstrated a solid hypoechoic nodule. FNA cytology was only suggestive of a lymphoproliferative disorder and did not provide a definitive diagnosis. It is core needle biopsy (CNB) that helped us to overcome the limitations of routine FNA cytology, showing the presence of thyroid Burkitt’s lymphoma. Subsequent staging demonstrated bone marrow involvement. The early start of an intensive multi-agent chemotherapy resulted in complete disease remission. At 60 months after the diagnosis, the patient is alive and has not had any recurrence. Conclusions Clinicians should be aware that thyroid Burkitt’s lymphoma is an aggressive disease that needs to be treated with multi-agent chemotherapy as soon as possible. To diagnose it promptly, they should consider to order/perform a CNB in any patient with a rapidly enlarging thyroid mass that is suspicious for lymphoma. |
Databáze: | OpenAIRE |
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